Monday, January 11, 2010

Airport Droids Attack Human Gene Pool

The Great Change
Tue, 29 Dec 2009 09:36 EST
"If it's something that's going to improve safety, then I don't have any problem with it, I have nothing to hide."
- Ashley Houston, 32, as she waited for a plane in Phoenix (Reuters).
If you were against transhumanism before, perhaps you should give it another look. Our bodies are the product of a billion years of nature's evolutionary processes, but the War on Terror is about to irrevocably corrupt our gene pool, causing untold immune system and other genetic damage to future generations, and possibly rendering the DNA coding that we are based on unacceptably toxic.

We may need to port our intelligence to a machine, or to cyberspace, if "human" intelligence is to survive in today's toxic environment.

While Homeland Security has installed Backscatter Advanced Imaging Technology (AIT) into airports while successfully avoiding an environmental impact statement, and the Justice Department is now fighting FOIA requests for technical specifications (filed by EPIC, Electronic Privacy Information Center), we already know that backscatter radiation may interfere directly with DNA. Although the ionizing radiation is small, the terahertz waves the machines generate do more than show your private parts to the screener. They have been found to "unzip double-stranded DNA, creating bubbles in the double strand that could significantly interfere with processes such as gene expression and DNA replication."

Radiation waves occur naturally in the environment, and we're hit with them all the time. But should we bombard ourselves with them unwillingly every time we want to board a flight? Initially the machines were supposed to be voluntary. Suddenly they are not.

The TSA issued a blog saying:
"Backscatter X-ray technology uses X-rays that penetrate clothing, but not skin, to create an image. Millimeter wave technology uses sensors to collect millimeter wave energy to measure the difference in radiated energy relative to each object against a common background (the human body produces these signatures in typical screening applications) to construct a composite image.

"For comparison purposes, the X-ray dose received from the backscatter system is equivalent to the radiation received in two minutes of airplane flight at altitude (.04 millirem by backscatter [2 scans] compared to .0552 millirem for two minutes of flight).

"The [non-ionizing radio frequency] energy projected by the system is 10,000 times less than a cell phone transmission (.00000597 mW/cm2 for millimeter wave technology compared to 37.5 mW/cm2 for a cellphone)."
We don't know about you, but whenever we hear a government agency use these kinds of comparisons we check our wallet.

Backscatter X-rays are nothing like the cosmic radiation we get at high altitudes, flights included. Nor is background radiation - or cellphone radiation - safe, thank you very much.

Medical science already knows how much terahertz radiation is safe for the body to absorb: none. You can think of it like sunlight - a little may be fine while a lot, you frequent flyers, may be deadly. However, where ionizing radiation is concerned, there is something called the superlinear dose response that wrecks that sunlight analogy. Middling range exposures are fine because they destroy the cells they hit. Low range exposures are far deadlier, because DNA is mutated but the cells survive to divide.

Our genome is smaller than that of an ear of corn, with about the same number of genes as an earthworm. DNA's secrets are not just in the genes, but in the way the code is arranged. In the human cell, certain chemical bonds are crucial to the integrity of the genetic code and breaking just a few of these bonds may endow the code with a permanent alteration. When a mutated gene is responsible for regulating normal cell growth, an uncontrolled proliferation of damaged cells, or cancer, can develop. When mutation occurs in the procreative cells or in the developing embryo, birth defects can result. When mutation occurs in the blood-forming tissue, impairment of the immune response system can result, and this can increase susceptibility to an entire spectrum of human disease.

Radiation is therefore said to be mutagenic (cell-mutating), carcinogenic (cancer-causing), teratogenic (birth-defect inducing), and immuno-suppressing (resistance-impairing). All of these effects, which begin at a submicroscopic level, remain invisible for extended periods of time until they reach observable proportions. The latent period may be decades in the case of an incipient cancer, or it may be centuries in the case of a genetic effect.

Even where the risk is very slight, if the population to be exposed is very large - several billion air-traveler-exposures annually - the epidemiological burden is overcome and real deaths result. Far more deaths, it may be (we won't know as long as FOIA immunity reigns) than deaths from terrorist air hijackings.

Most predictive models also make the assumption that the exposed population is homogeneous. In fact, there are subgroupings for susceptibility in the population, and equal radiation exposure can increase disease by five to ten times in the more susceptible groups over the less susceptible. All men are not created equal, and the burden of environmental radioactivity will fall more heavily on some than on others, depending on their genes. Children are very vulnerable. Fetuses even more so. As the Nuclear Regulatory Commission has acknowledged,
"Because our present state of knowledge precludes all possible meaningful quantifications of the relative radiosensitivity of a given individual, it is true that persons are not necessarily equally 'protected' by current federal regulations designed to protect the general population as a whole."
- - Jeannine Honicker v. United States of America, et al.
One concept of the genetic mutation process put forward by the National Academy of Sciences employed a line of nucleoproteins in a normal sequence something like this: AGT-AGT-AGT-AGT-AGT-AGT-AGT.... In this model the DNA code is read and transmitted in groups of three proteins. Consider what happens if the sequence is disturbed, such as when a speeding terahertz wave dislodges one protein in the chain. The entire sequence is thrown off until two counterbalancing breaks occur that throw it back into correct order. Until then it is read: AG-TAG-TAG-TAG-TAG-TAG-TAG....

Suppose the AGT sequence was for brain cells, but the TAG sequence was for stomach muscles. You could get something pretty weird happening. It may have been from mutations such as these that all of us evolved. As a species, we arrived at our present form by selection of favorable mutations and elimination of unfavorable mutations, which is not to say it was a pleasant process for those individuals with the unfavorable mutations. The rate of genetic translocations in humans caused by ionizing radiation and estimated in the current the scientific literature ranges from 24 to 1,330 translocations per unit of radiation (rad) per million live births per generation. It takes on the order of 100 generations to eliminate each unfavorable mutation from the genetic pool, whether it is for a fruit fly or a baboon.

Biostatistician Rosalie Bertell has suggested that elevation of the background level of mutagens in combination with mutations which interfere with normal reproduction could result in sudden species extinction, which, if the species is humans, by the time we recognized the threat, we could be powerless to counter.

The US Supreme Court has marked this territory with a bright line. Where rights to be protected are clearly enumerated, are "so rooted in the traditions and conscience of the nation as to be ranked as fundamental," or are "implicit in the concept of ordered liberty," so that failure to protect them would mark a departure from first principles, federal authority should be conditioned upon the demonstration of an overriding interest of compelling importance, the absence of less damaging alternatives for meeting that interest, and some method of limiting or restricting the scope of the excursion and redressing the injustice created.

Over the past decade, in the United States alone, we've had sixteen million flights that got to their destinations without incident for every flight that was victimized by crime. Should we punish the millions of safe passengers to deter the one criminal? Should we sacrifice our future genetic heritage for the sake of an abstract, and likely unobtainable, perfection of our "security?"

How we define security matters. We should force ourselves to thoroughly examine alternatives in the future before embarking upon any new governmental encroachments, or putting new wrinkles on old encroachments, that carry species-ending health implications.

And Mr. Obama, tear down that secrecy wall.

How Terahertz Waves Tear Apart DNA

Technology Review
Fri, 30 Oct 2009 09:20 EDT
A new model of the way the THz waves interact with DNA explains how the damage is done and why evidence has been so hard to gather.

Great things are expected of terahertz waves, the radiation that fills the slot in the electromagnetic spectrum between microwaves and the infrared. Terahertz waves pass through non-conducting materials such as clothes, paper, wood and brick and so cameras sensitive to them can peer inside envelopes, into living rooms and "frisk" people at distance.

The way terahertz waves are absorbed and emitted can also be used to determine the chemical composition of a material. And even though they don't travel far inside the body, there is great hope that the waves can be used to spot tumours near the surface of the skin.

With all that potential, it's no wonder that research on terahertz waves has exploded in the last ten years or so.

But what of the health effects of terahertz waves? At first glance, it's easy to dismiss any notion that they can be damaging. Terahertz photons are not energetic enough to break chemical bonds or ionise atoms or molecules, the chief reasons why higher energy photons such as x-rays and UV rays are so bad for us. But could there be another mechanism at work?

The evidence that terahertz radiation damages biological systems is mixed. "Some studies reported significant genetic damage while others, although similar, showed none," say Boian Alexandrov at the Center for Nonlinear Studies at Los Alamos National Laboratory in New Mexico and a few buddies. Now these guys think they know why.

Alexandrov and co have created a model to investigate how THz fields interact with double-stranded DNA and what they've found is remarkable. They say that although the forces generated are tiny, resonant effects allow THz waves to unzip double-stranded DNA, creating bubbles in the double strand that could significantly interfere with processes such as gene expression and DNA replication. That's a jaw dropping conclusion.

And it also explains why the evidence has been so hard to garner. Ordinary resonant effects are not powerful enough to do do this kind of damage but nonlinear resonances can. These nonlinear instabilities are much less likely to form which explains why the character of THz genotoxic effects are probabilistic rather than deterministic, say the team.

This should set the cat among the pigeons. Of course, terahertz waves are a natural part of environment, just like visible and infrared light. But a new generation of cameras are set to appear that not only record terahertz waves but also bombard us with them. And if our exposure is set to increase, the question that urgently needs answering is what level of terahertz exposure is safe.

Ref: arxiv.org/abs/0910.5294: DNA Breathing Dynamics in the Presence of a Terahertz Field

Backscatter x-ray machines "tear apart DNA"

Yahoo! Tech
Fri, 30 Oct 2009 09:04 EDT
The latest airport security trend is the backscatter x-ray machine, touted as a powerful way to virtually frisk a traveler for contraband without the embarassment of a strip search.

Though touted as completely safe because the level of radiation is so low, travelers have been nervous about the devices -- and not just because it shows off a nice outline of their privates to the people manning the machines -- but because they remain scared of the health problems they might propose.

Looks like a little healthy paranoia might have been a good thing. While the conventional wisdom has held that so-called "terahertz radiation," upon which backscatter x-ray machines are based, is harmless because it doesn't carry enough energy to do cellular or genetic damage, new research suggests that may be completely wrong.

Specifically, researchers have found that terahertz radiation may interfere directly with DNA. Although the force generated is small, the waves have been found to "unzip double-stranded DNA, creating bubbles in the double strand that could significantly interfere with processes such as gene expression and DNA replication."

I'm not a doctor, but that just doesn't sound good.

The question now is whether this is or isn't safe. Terahertz waves occur naturally in the environment, and we're hit with them all the time. But should we bombard ourselves with them willingly every time we pass through an airport? No one knows how much terahertz radiation is OK for the body to absorb: Just like sunlight, a little may be fine, while a lot may be deadly. Where does the line get drawn?

Who knows? I, for one, am given a little pause by the news, and hope research continues on before these machines become commonplace.